Rob Allen, an active Zend Framework developer and writer, recently explained how to setup PHP and MySQL on the latest version of Mac OS X, 10.8 (aka Mountain Lion). The article does assume some comfort with using the Terminal application (i.e., working with the command line), but goes through everything you need to know, including installing and enabling several common needs. If you’re using Mountain Lion and don’t want to go the MAMP route (I’ve stopped using MAMP and other all-in-one packages myself), this article should be everything you need.